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Abstract #4138

Interventional MRI-Guided Local Delivery of Agents into Swine Bile Duct Walls Using MR Compatible Needle-Integrated Balloon Catheter System

Feng Zhang 1 , Zhibin Bai 1 , Yaoping Shi 1 , Jianfeng Wang 1 , Longhua Qiu 1 , Yonggang Li 1 , and Xiaoming Yang 1

1 Radiology, University of Washington, SEATTLE, WA, United States

Systemic chemotherapy has limited therapeutic effect on pancreatobiliary cancers due to the insufficient drugs delivered to the tumors. To address this problem, we successfully developed a technique of using interventional magnetic resonance imaging (MRI) to guide intrabiliary agent delivery into pig common bile duct (CBD) walls with a newly-designed MR compatible needle-integrated balloon catheter system.

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