Abstract #4165
Investigation of In-vivo Relationship between Cartilage Contact and Cartilage Quantitative MR Parameters
Fang Liu 1 , Jarred Kaiser 2 , Walter F. Block 1,3 , Darryl G. Thelen 2,3 , and Richard Kijowski 4
1
Department of Medical Physics, University of
Wisconsin-Madison, Madison, Wisconsin, United States,
2
Department
of Mechanical Engineering, University of
Wisconsin-Madison, Madison, Wisconsin, United States,
3
Department
of Biomedical Engineering, University of
Wisconsin-Madison, Madison, Wisconsin, United States,
4
Department
of Radiology, University of Wisconsin-Madison, Madison,
Wisconsin, United States
A novel dynamic and static MR method was proposed to
investigate the in-vivo relationship between cartilage
contact and quantitative cartilage MR parameters in an
asymptomatic subject following anterior cruciate
ligament reconstruction surgery. A cartilage contact map
of the tibia plateau was created using dynamic SPGR-VIPR
imaging performed during active loaded knee flexion and
extension, cartilage thickness map was created using 3D
fast spin-echo imaging, and cartilage single-component
T2 and fast relaxing water fraction (Ff) maps were
created using mcDESPOT imaging. Cartilage contact was
found to positively correlate with cartilage thickness
and cartilage Ff and negatively correlate with cartilage
T2.
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