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Abstract #4170

Highly-Accelerated 3D T1rho Mapping of the Knee Using k-t SPARSE-SENSE

Ding Xia 1,2 , Li Feng 1,2 , Tiejun Zhao 3 , and Ravinder R. Regatte 1,2

1 Center for Advanced Imaging Innovation and Research (CAI2R), Department of Radiology, New York University School of Medicine, New York, NY, United States, 2 Bernard and Irene Schwartz Center for Biomedical Imaging, Department of Radiology, New York University School of Medicine, New York, NY, United States, 3 Siemens Medical Solution USA. Inc, New York, NY, United States

This work investigates the feasibility of highly-accelerated 3D-T1rho mapping in human knee cartilage using a combination of compressed sensing and parallel imaging. Fully sampled dynamic k-space data were retrospectively undersampled at different acceleration rates from 2 to 6 and reconstructed using k-t SPARSE-SENSE, a reconstruction framework that exploits joint multicoil sparsity in dynamic imaging. The 3D T1rho maps estimated from the accelerated datasets was compared with the fully sampled reference. Accurate T1rho maps can be obtained up to 5-fold acceleration, which suggest that the proposed approach could be useful in assessing musculoskeletal diseases such as osteoarthritis with reduced scan times.

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