Abstract #4180
Optimization of adiabatic T 1 and T 2 for quantification of articular cartilage at 3T
Victor Casula 1,2 , Mikko J. Nissi 3,4 , Joonas Autio 3 , Michaeli Shalom 4 , Silvia Mangia 4 , Edward Auerbach 4 , Jutta Ellermann 4 , Eveliina Lammentausta 3 , and Miika T. Nieminen 1,3
1
Radiology, University of Oulu, Oulu, Oulu,
Finland,
2
Medical
Research Center Oulu, Oulu University Hospital and
University of Oulu, Oulu, Oulu, Finland,
3
Department
of Diagnostic Radiology, Oulu University Hospital, Oulu,
Finland,
4
Center
for Magnetic Resonance Research, Department of
Radiology, University of Minnesota, Minneapolis, United
States
Adiabatic T
1
and
T
2
sequences
were evaluated with a 3 T clinical system. The optimal
parameters for in vivo quantitative imaging of articular
cartilage were determined on the basis of the evaluation
of relaxation time maps and in order to minimize
scanning time and power deposition and maximize image
quality. The results show that adiabatic T
1
and
adiabatic T
1
are
suitable for in vivo quantitative assessment of
articular cartilage at 3 T. The preliminary results are
encouraging when the techniques were applied to
discriminate normal and early osteoarthritis cartilage.
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