Relaxation time constants T1 and T2* of bound and free water in cortical bone at 600 MHz and 700 MHz.
Bainan Wu 1 , Robert Nikolov 2 , Hongda Shao 2 , Jun Chen 2 , Graeme Bydder 2 , Maurizio Pellecchia 1 , and Jiang Du 2
Sanford-Burnham Medical Research Institute,
La Jolla, California, United States,
University of California, San Diego, San Diego,
California, United States
The purpose of this study is to measure and report the
field dependence of NMR relaxation times (T* and T1) of
the free and bound water in cortical bone at magnetic
field strenghts corresponding to frequencies of 600 MHz
and 700MHz. T2* of bound/free water is measured to be
6.2(0.1)s /80(3)s at 600MHz and decreases to
5.4(0.1)s /63(5)s at 700 MHz. T1 of bound/free water
is reported to be 628/632ms at 600 MHz and 661/672 ms at
700 MHz. At both field strengths, the free water
contributes to about 10% of the NMR signal.
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