Importance of Supine Rest Period before Imaging for Thigh Muscle Volume Quantification

This study aimed to evaluate the influence of supine rest on thigh muscle volume in a healthy volunteer. Dynamic T1-weighted MR images were acquired in the mid-thigh region for 30 minutes. On average, muscle volume in the mid-thigh region decreased by 1.21%. The average coefficient-of-variation of two consecutive acquisitions was 0.15%, indicating that the measurement technique should be sensitive to changes in volume of less than 1%. At least 15 minutes of supine rest prior to positioning on the table may help to detect smaller changes in the thigh muscle volume by eliminating variability that could be introduced by redistribution of fluid in the muscles when posture is changed.

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