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Abstract #4384

Diffusion-weighted MR Imaging Using Mono-exponential, Bi-exponential and Mono-exponential high-b values Models in the Grading of Gliomas

Yan Bai 1 , Carlos Torres 2 , Zhoushe Zhao 3 , Dandan Zheng 3 , Dapeng Shi 1 , Jie Tian 4 , and Meiyun Wang 1

1 Henan Provincial People's Hospital, Zhengzhou, Henan, China, 2 Department of Radiology, The Ottawa Hospital, The University of Ottawa, Ottawa, ON, Canada, 3 GE Healthcare, Beijing, China, 4 Institute of Automation, Chinese Academy of Sciences, Beijing, China

This study evaluated and compared the potential of diffusion-weighted imaging (DWI) using mono-exponential, bi-exponential and mono-exponential high-b values models in the grading of gliomas. The results suggested that multi-model DWI is useful in the grading of gliomas. ADChigh may become a novel parameter to reflect AQP4 expression in gliomas and guiding personalized treatment.

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