Abstract #4414
Multiparametric MRI characterization of mild traumatic brain injury in mice
Yichu Liu 1,2 , Lora Watts 1 , Qiang Shen 1 , Hemanth Manga 1,2 , and Timothy Duong 1
1
Research Imaging Center, University of Texas
Health Science Center, San Antonio, Texas, United
States,
2
Biomedical
Engineering, UT San Antonio, San Antonio, Texas, United
States
The goal of this study was to use multiparametric MRI
(T2, CBF, ADC, and FA) to longitudinally characterize
the spatiotemporal dynamics during hyperacute and
subacute mild traumatic brain injury (TBI) in mice. The
impact was targeted to the left primary forelimb
somatosensory cortex. Comparisons were made with
functional assessment measured by the forelimb asymmetry
test. Moreover, comparisons were also made with
published rat mild TBI data under essentially
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