Abstract #4434
Large-FOV Tractography of the Brain and Spinal Cord with Reduced Scan Time: A Study using Diffusion-Weighted, Readout-Segmented EPI and Simultaneous Multi-Slice Acceleration
Wei Liu 1 , Himanshu Bhat 2 , Julien Cohen-Adad 3 , Kawin Setsompop 4 , Dingxin Wang 5 , Thomas Beck 6 , Stephen F. Cauley 4 , Kun Zhou 1 , and David A. Porter 7
1
Siemens Shenzhen Magnetic Resonance Ltd.,
Shenzhen, Guangdong, China,
2
Siemens
Medical Solutions USA, Inc., Charlestown, MA, United
States,
3
Department of Electrical Engineering,
Institute of Biomedical Engineering, Ecole Polytechnique
de Montreal, Montreal, QC, Canada,
4
A.A.
Martinos Center for Biomedical Imaging, Dept. of
Radiology, MGH, Charlestown, MA, United States,
5
Siemens
Medical Solutions USA, Inc., Minneapolis, MN, United
States,
6
MR
Application Development, Siemens Healthcare, Erlangen,
Germany,
7
Fraunhofer
MEVIS, Institute for Medical Image Computing, Bremen,
Germany
Readout-segmented EPI (rs-EPI) is an established
clinical technique for acquiring DW images with reduced
distortion and T2*-related blurring, which is therefore
particularly well-suited to acquire high-quality DW data
from the whole brain and cervical spine. However, the
acquisition time increases with the number of readout
segments. In this study, we demonstrate how the
blipped-CAIPIRINHA simultaneous multi-slice technique
can be used with rs-EPI to provide a unique method for
performing rapid tractography studies of the brain and
spinal cord with low distortion and a large anatomical
coverage, whilst preserving data quality for
tractography studies.
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