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Abstract #4447

High-resolution three-dimensional ANGIE T1 mapping of the heart

Bhairav Bipin Mehta 1 , Michael Salerno 1,2 , and Frederick H Epstein 1,3

1 Department of Biomedical Engineering, University of Virginia, Charlottesville, Virginia, United States, 2 Department of Medicine, Cardiology Division, University of Virginia, Charlottesville, Virginia, United States, 3 Department of Radiology and Medical Imaging, University of Virginia, Charlottesville, Virginia, United States

Assessment of fibrosis in thin structures such as the right ventricular (RV) and left atrial walls would be valuable in various disorders. However, current cardiac T1 mapping techniques have limited spatial resolution for these applications. We previously developed a 2D sequence, ANGIE, which enables high-resolution T1 mapping. However, high resolution 2D imaging is limited by low SNR and time efficiency. In the present study, we extend ANGIE to perform high-resolution three-dimensional (3D) T1 mapping of the heart within a clinically acceptable scan time. 3D ANGIE was evaluated by performing comparisons with 2D ANGIE and 2D MOLLI in six healthy volunteers.

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