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Abstract #4451

Free-breathing myocardial 3D T1 mapping using inversion time specific image-based respiratory navigators

Markus Henningsson 1 , Rene Botnar 1 , and Tobias Voigt 1,2

1 Division of Imaging Sciences and Biomedical Engineering, King's College London, London, United Kingdom, 2 Clinical Research Europe, Philips Research, Hamburg, United Kingdom

Free-breathing whole-heart myocardial T1 mapping is technically challenging due to the difficulty of respiratory motion compensation. Conventional respiratory gating techniques are impractical due to the prolonged scan time associated with these approaches. In this work we propose an image-based navigator approach which allows for direct tracking of the respiratory motion of the heart. Although this means navigators at different inversion times have different contrast, potentially leading to registration errors, we solve this problem by using a separate navigator reference for each inversion time. We evaluate this free-breathing three-dimensional T1-mapping method in 7 healthy volunteers and compared it to 2D T1-mapping.

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