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Abstract #4459

3D Late Gadolinium Enhancement Imaging using CENTRA-PLUS ordering with Weighted Navigator Acquisition: Feasibility of Surgically Implanted RV Patch Volume Quantification in Swine Model

Keigo Kawaji 1 , Akiko Tanaka 2 , Mita Patel 1 , Sui-Cheng Wang 3 , Hui Wang 4 , Takeyoshi Ota 2 , Roberto M. Lang 1 , and Amit R. Patel 1

1 Medicine, Section of Cardiology, The University of Chicago, Chicago, Illinois, United States, 2 Surgery, The University of Chicago, Chicago, Illinois, United States, 3 Biomedical Engineering, Northwestern University, Evanston, Illinois, United States, 4 Philips Medical Systems, Cleveland, Ohio, United States

In this study, we propose a novel ECG-triggered and navigator-gated 3D LGE acquisition method that uses CENTRA-PLUS profile/view ordering that is designed to acquires central and peripheral k-space with a weighted navigator gating window. Six pigs were surgically implanted with Right Ventricular (RV) patches, and MRI was performed 7-9 weeks after surgery. RV patch volume quantification was performed using both 2D PSIR LGE and the proposed 3D PSIR LGE images, and volume measurement errors were compared to the gold standard direct measurements made on the surgically excised RV patch region.

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