Abstract #4461
The Accuracy of Quantitative MR Elastography in an Anatomically Accurate Diastolic Cardiac Phantom
Arvin Arani 1 , Shivaram Poigai Arunachalam 1 , Phillip Rossman 1 , Armando Manduca 2 , David S. Lake 1 , Joshua D. Trzasko 1 , Kiaran P. McGee 1 , Kevin J Glaser 1 , Richard L. Ehman 1 , and Philip Araoz 1
1
Radiology, Mayo Clinic, Rochester,
Minnesota, United States,
2
Physiology
and Biomedical Engineering, Mayo Clinic, Rochester,
Minnesota, United States
Normal cardiac function is dependent on the mechanical
properties of the myocardium, which may serve as a
valuable predictor of disease. Several groups have
investigated the use of MR Elastography to measure
stiffness in vivo. However, a thorough evaluation of the
accuracy of the reported stiffness measurements and the
optimal experimental settings has not been well
established. The purpose of this work, was to evaluate
the accuracy of 3D MRE direct inversion at multiple
frequencies, on curl wave fields in a morphologically
accurate left ventricular phantom using dynamic
mechanical testing (DMA) as the reference standard.
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