Can we rely on the new 1T benchtop systems for investigating cardiac function and viability?
Daniel James Stuckey 1 , Thomas A Roberts 1 , Laurence H Jackson 1 , Rajiv Ramasawmy 1 , Valerie Taylor 1 , Anna L David 2 , Bernard Siow* 1 , and Mark F Lythgoe* 1
Centre for Advanced Biomedical Imaging, UCL
- University College London, London, United Kingdom,
for Womens Health, UCL - University College London,
London, United Kingdom
We show for the first time that 1T benchtop MRI can
assess myocardial viability as well as contraction in a
rat model of myocardial infarction. Results compared
well with high field MRI and ultrasound. Although the
speed with which ultrasound acquisitions can be acquired
make it an effective choice for rapidly measuring
cardiac contractility, the ability of MRI to rapidly
quantify infarct size using late gadolinium enhancement,
as well as RV function, demonstrates that low field MRI
systems can provide essential information beyond what is
possible from ultrasound, making it a valuable tool for
studying experimental myocardial infarction and therapy.
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