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Abstract #4481

Can we rely on the new 1T benchtop systems for investigating cardiac function and viability?

Daniel James Stuckey 1 , Thomas A Roberts 1 , Laurence H Jackson 1 , Rajiv Ramasawmy 1 , Valerie Taylor 1 , Anna L David 2 , Bernard Siow* 1 , and Mark F Lythgoe* 1

1 Centre for Advanced Biomedical Imaging, UCL - University College London, London, United Kingdom, 2 Institute for Womens Health, UCL - University College London, London, United Kingdom

We show for the first time that 1T benchtop MRI can assess myocardial viability as well as contraction in a rat model of myocardial infarction. Results compared well with high field MRI and ultrasound. Although the speed with which ultrasound acquisitions can be acquired make it an effective choice for rapidly measuring cardiac contractility, the ability of MRI to rapidly quantify infarct size using late gadolinium enhancement, as well as RV function, demonstrates that low field MRI systems can provide essential information beyond what is possible from ultrasound, making it a valuable tool for studying experimental myocardial infarction and therapy.

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