Abstract #4491
Fusion and combined evaluation of 3D-CMR-perfusion with 3D-MR-coronary angiography
Alexander Gotschy 1,2 , Lukas Wissmann 1 , Datta Singh Goolaub 1 , Markus Niemann 3 , Sebastian Kozerke 1 , and Robert Manka 1,3
1
Institute for Biomedical Engineering,
University and ETH Zurich, Zurich, Switzerland,
2
Department
of Internal Medicine, University Hospital Zurich,
Zurich, Switzerland,
3
Department
of Cardiology, University Hospital Zurich, Switzerland
The most relevant parameters for the assessment of
coronary artery disease are myocardial perfusion and the
status of the coronary arteries. Therefore, the aim of
our study was to investigate the feasibility and
potential added value of MR-based hybrid imaging by the
combined assessment and fusion of 3D-MR coronary
angiography (MRCA) with a 3D-CMR-perfusion sequence. We
found that the combined evaluation had superior
sensitivity at the cost of a loss in specificity when
compared to CMR-perfusion alone in a vessel-based
approach. Furthermore in the fused images, coronary
stenosis could be matched with perfusion deficits in
different myocardial layers.
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