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Abstract #4491

Fusion and combined evaluation of 3D-CMR-perfusion with 3D-MR-coronary angiography

Alexander Gotschy 1,2 , Lukas Wissmann 1 , Datta Singh Goolaub 1 , Markus Niemann 3 , Sebastian Kozerke 1 , and Robert Manka 1,3

1 Institute for Biomedical Engineering, University and ETH Zurich, Zurich, Switzerland, 2 Department of Internal Medicine, University Hospital Zurich, Zurich, Switzerland, 3 Department of Cardiology, University Hospital Zurich, Switzerland

The most relevant parameters for the assessment of coronary artery disease are myocardial perfusion and the status of the coronary arteries. Therefore, the aim of our study was to investigate the feasibility and potential added value of MR-based hybrid imaging by the combined assessment and fusion of 3D-MR coronary angiography (MRCA) with a 3D-CMR-perfusion sequence. We found that the combined evaluation had superior sensitivity at the cost of a loss in specificity when compared to CMR-perfusion alone in a vessel-based approach. Furthermore in the fused images, coronary stenosis could be matched with perfusion deficits in different myocardial layers.

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