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Abstract #4498

Comprehensive arterial assessment in diabetic patients using combined quiescent interval single shot (QISS) imaging for leg imaging and QISS-arterial spin labeled MRA for pedal imaging: preliminary experience with comparison to DSA

Ruth P Lim 1,2 , Adrienne CY Lam 1 , Matthew Lukies 1 , Dinesh Ranatunga 1 , Emma K Hornsey 1 , Brenden McColl 1 , Yuliya Perchyonok 1,2 , Jason Chuen 2,3 , Jason Heidrich 1 , Pei-Heng Ko 3 , and Robert R Edelman 4

1 Radiology, Austin Health, Melbourne, Victoria, Australia, 2 The University of Melbourne, Melbourne, Victoria, Australia, 3 Vascular Surgery, Austin Health, Melbourne, Victoria, Australia, 4 Radiology, NorthShore University Health System, Chicago, IL, United States

Imaging peripheral arterial disease (PAD) in diabetic patients is challenging. We evaluate a combined QISS MRA and QISS arterial spin labeled MRA approach (cQISS MRA) for imaging from the infrarenal aorta to the pedal vessels in 15 diabetic patients with symptomatic PAD, using digital subtraction angiography as the reference standard. High diagnostic confidence was observed for cQISS-MRA, however this was significantly lower in the foot compared to more proximal regions. 74.7% sensitivity and 86.8% specificity for hemodynamically significant (≥50%) stenosis was observed overall, with highest sensitivity and specificity for the pelvic region, and poor specificity (50%) for the pedal region.

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