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Abstract #4528

An Integer Optimization Technique for Measuring Biventricular Cardiac Strain from Tagged MR Images

Ming Li 1,2 , Himanshu Gupta 3 , Steven G. Lloyd 3 , Louis J. Dell'Italia 3 , and Thomas S. Denney Jr. 1,2

1 Auburn University MRI Research Center, Auburn University, Auburn, AL, United States, 2 Electrical and Computer Engineering, Auburn University, AL, United States, 3 Division of Cardiovascular Disease, University of Alabama at Birmingham, AL, United States

In this abstract we propose an integer optimization based method for unwrapping harmonic phase from tagged cardiac MR images and use this method to compute 3D biventricular cardiac strain through the cardiac cycle. Compared to the traditional quality guided phase unwrapping method, the proposed method was considerably less sensitive to the phase inconsistencies and therefore required less manual intervention. 5 min of automated phase unwrapping and 15 min of manual corrections were required for each study. Biventricular strains from the proposed method were compared to both a feature-based and a phase-based method.

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