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Abstract #0003

Quantitative evaluation of eddy-current and motion correction techniques for diffusion-weighted MRI

Mark S Graham1, Ivana Drobnjak1, and Hui Zhang1

1Centre for Medical Image Computing & Department of Computer Science, UCL, London, United Kingdom

It is necessary to perform correction of eddy-current and motion artefacts before analysing DW-MR data, but none of the commonly used correction techniques have been evaluated quantitatively using direct measures of correspondence. Here we apply a recently proposed simulation framework to evaluate four correction techniques. We found the three techniques that register to a b=0 image (Eddy_correct, ACID, ExploreDTI) perform worse than a technique that registers to predicted DWIs (eddy). Furthermore, we found that one of the most commonly used methods for registration to b=0, eddy_correct, performs significantly worse than the other methods considered.

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