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Abstract #0068

Effect of temporal resolution and serial autocorrelations in fast fMRI

Ashish Kaul Sahib1, Klaus Mathiak2, Michael Erb1, Adham Elshahabi3, Silke Klamer3, Klaus Scheffler4, Niels Focke3, and Thomas Ethofer1

1Biomedical magnetic resonance, University of tuebingen, Tuebingen, Germany, 25Department of Psychiatry, Psychotherapy and Psychosomatics, University Hospital Aachen, Aachen, Germany, 3Department of Neurology/Epileptology, University of tuebingen, Tuebingen, Germany, 4Max-Planck-Institute for Biological Cybernetics, Tuebingen, Germany

To assess the impact of colored noise on statistics and determine optimal imaging parameters in event-related fMRI (visual stimulation using checkerboards) acquired by simultaneous multi-slice imaging enabling repetition times (TR) between 2.64 to 0.26s. Optimal statistical power was obtained for a TR of 0.33s, but short TRs required higher-order autoregressive (AR) models to achieve stable statistics. Colored noise in event-related fMRI obtained at short TRs calls for more sophisticated correction of serial autocorrelations.

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