Abstract #0128

Role of the Intravoxel Incoherent Motion (IVIM) Imaging in the Pre-treatment Prediction and Early Response Monitoring for Neoadjuvant Chemotherapy in Locally Advanced Breast Cancer

Shunan Che¹, Chunwu Zhou¹, Xinming Zhao¹, Jing Li¹, and Bing Wu²

¹department of radiology, Cancer Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China, People's Republic of, ²GE Healthcare MR Research China, Beijing, China, People's Republic of

Purpose: to explore whether IVIM can determine pre-treatment differences or monitor early response in breast cancer patients receiving NAC. Materials and Methods: thirty-six patients examined with multiple-b DWI were divided into MHR and NMHR groups. Parameters between MHR and NMHR groups were compared. Results: the D and f value at the baseline and mid-treatment of NAC showed significantly differences between MHR and NMHR. △D and △f were significantly higher in MHR than in NMHR. Conclusion: the D and f value showed potential value in the pre-treatment prediction and early response monitoring to NAC in local advanced breast.

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