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Abstract #0209

Experimental detection of imaginary signals in diffusion pore imaging using double diffusion encoding

Kerstin Demberg1, Frederik Bernd Laun1, Johannes Windschuh1, Reiner Umathum1, Peter Bachert1, and Tristan Anselm Kuder1

1Medical Physics in Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany

By diffusion pore imaging, the average shape of arbitrary closed pores in an imaging volume element can be detected employing a long-narrow gradient profile. Alternative approaches use short gradient pulses only. Until now, however, diffusion pore imaging of non-point-symmetrically shaped pores has not been demonstrated using short gradient pulses only. In this abstract, we present a first experimental verification using double diffusion encoded experiments. Non-point-symmetric pores result in non-vanishing imaginary parts in the double diffusion encoded signal. Thus the phase of the form factor can be estimated with an iterative approach. This allows for unambiguous pore image reconstruction.

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