Csanad Varallyay1, Daniel Schwartz2, Joao Prola Netto1, Prakash Ambady2, Andrea Horvath2, and Edward Neuwelt2
1Diagnostic Radiology and Neurology, Oregon Health and Science University, Portland, OR, United States, 2Neurology, Oregon Health and Science University, Portland, OR, United States
Steady state blood volume (SS-CBV) mapping using the blood
pool agent ferumoxytol as an MRI contrast agent is feasible in brain tumors and
other intracranial pathologies. It allows high resolution, distortion
free blood volume maps, which can be a useful MRI tool to improve diagnosis and assessment of response to therapy. Ferumoxytol dose and MRI sequences may be optimized for various clinical applications.