Abstract #0304

Implementing single-shot quantitative CEST/T1ρ measurements using bSSFPX

Shu Zhang¹, Robert E Lenkinski^1,2, and Elena Vinogradov^1,2

¹Radiology, UT Southwestern Medical Center, Dallas, TX, United States, ²Advanced Imaging Research Center, UT Southwestern Medical Center, Dallas, TX, United States

Recently properties of bSSFP were explored to detect exchange processes (bSSFPX), similar to CEST or off-resonance T_1ρ experiments. We expand the study and implement a transient bSSFPX experiment that acquires bSSFP spectra continuously as the effective saturation time increases, allowing observation of the approach of magnetization to the steady state in a single shot. The magnetization dynamic is governed by the effective field and relaxation times parallel or perpendicular to it. Work is in progress to derive an exact quantification model. The method leads to fast acquisition of time-dependent data and may speed up QUEST-like quantification of the exchange processes.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.