Abstract #0378

Multi-Band MRSI at 7T using 3D B1 Shimming based Outer Volume Suppression

Hoby Patrick Hetherington¹, Tiejun Zhao², Victor Yushmanov¹, and Jullie Pan³

¹Radiology, University of Pittsburgh, Pittsburgh, PA, United States, ²Siemens Medical Systems, New York, NY, United States, ³Neurology, University of Pittsburgh, Pittsburgh, PA, United States

To provide near whole brain coverage for both anatomical imaging and MRSI we used an 8x2 transceiver array with 8 independent RF channels and eight 1 to 2 splitters. This configuration provided a homogeneous RF distribution (<12% SD, 750Hz peak B1) while enabling 3D RF shimming based outer volume suppression to minimize extra-cerebral lipid signals. MRSI data was acquired at 7T from control subjects and patients with mTBI with a multi-band MRSI sequence (four simultaneous slices) using two RF distributions. Increases in choline/NAA were seen in both the anterior frontal lobe and the hippocampi.

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