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Abstract #0378

Multi-Band MRSI at 7T using 3D B1 Shimming based Outer Volume Suppression

Hoby Patrick Hetherington1, Tiejun Zhao2, Victor Yushmanov1, and Jullie Pan3

1Radiology, University of Pittsburgh, Pittsburgh, PA, United States, 2Siemens Medical Systems, New York, NY, United States, 3Neurology, University of Pittsburgh, Pittsburgh, PA, United States

To provide near whole brain coverage for both anatomical imaging and MRSI we used an 8x2 transceiver array with 8 independent RF channels and eight 1 to 2 splitters. This configuration provided a homogeneous RF distribution (<12% SD, 750Hz peak B1) while enabling 3D RF shimming based outer volume suppression to minimize extra-cerebral lipid signals. MRSI data was acquired at 7T from control subjects and patients with mTBI with a multi-band MRSI sequence (four simultaneous slices) using two RF distributions. Increases in choline/NAA were seen in both the anterior frontal lobe and the hippocampi.

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