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Abstract #0422

Using 3D ASL to assess the change of cerebral blood flow at high altitude: a longitudinal study

Wenjia Liu1, Bing Wu2, Dandan Zheng2, Xin Lou1, Yulin Wang1, Li Zheng3, Jie Liu4, and Lin Ma1

1Department of Radiology, PLA General Hospital, Beijing, China, People's Republic of, 2GE Healthcare, MR Research China, Beijing, Beijing, China, People's Republic of, 3Biomedical Engineering, Peking university, Beijing, China, People's Republic of, 4General Hospital of Tibetan Military Area Command, Lhasa, China, People's Republic of

Although cerebral blood flow(CBF) at high altitude have been researched for years, most previous studies are limited by the use of transcranial Doppler. The conclusion of changes in CBF depend on the assumption that the middle cerebral arterial diameter does not alter in hypoxia, but recent studies suggesting that this is not the case. In our study, CBF was measured by 3D arterial spin labeling (ASL) technique at sea level and high altitude in order to seek the cerebrovascular response to altitude environment.

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