Abstract #0463

A new hybrid approach for quantitative multi-slice myocardial DCE perfusion

Edward DiBella¹, Devavrat Likhite¹, Ganesh Adluru¹, Chris Welsh¹, and Brent Wilson¹

¹University of Utah, Salt Lake City, UT, United States

Here we propose a unique perfusion acquisition that uses one saturation pulse per heartbeat. This combined with simultaneous multi-slice (SMS) methods allows for acquiring the same set of slices continuously through the cardiac cycle. This has a number of advantages including the ability to retrospectively reconstruct an accurate arterial input function (AIF) and optimized systolic/diastolic frames, or other portions of the cardiac cycle. The approach proposed here acquires both k-space rays that reflect the influence of the saturation pulse and other rays that reflect the steady-state GRE contrast, and thus is termed the “hybrid” method. Preliminary quantitative results including comparisons to more standard methods in two subjects show the promise of this SMS approach.

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