Meeting Banner
Abstract #0568

Simultaneous T2, T2' and PDFF mapping in the spine using an adiabatic T2-prepared time-interleaved multi-echo gradient echo acquisition

Stefan Ruschke1, Dominik Weidlich1, Maximilian Diefenbach1, Holger Eggers2, Hendrik Kooijman3, Houchun H. Hu4, Ernst J. Rummeny1, Axel Haase5, Jan S. Kirschke6, Thomas Baum1, and Dimitrios C. Karampinos1

1Department of Diagnostic and Interventional Radiology, Technische Universität München, Munich, Germany, 2Philips Research, Hamburg, Germany, 3Philips Healthcare, Hamburg, Germany, 4Radiology, Phoenix Children’s Hospital, Phoenix, AZ, United States, 5Zentralinstitut für Medizintechnik, Technische Universität München, Garching, Germany, 6Neuroradiology, Technische Universität München, Munich, Germany

Simultaneous T2 and T2ʹ mapping is highly desirable in applications investigating changes in blood oxygenation, iron content and bone mineral density. Simultaneous T2 and T2ʹ mapping is highly desirable in applications investigating blood oxygenation changes (in tumors), iron deposition (in patients with blood transfusions) and trabecular bone matrix weakening (in osteoporosis patients). Gradient echo imaging using adiabatic T2-preparation has enabled T2 mapping in the presence of inhomogeneous B1 fields. In addition, the presence of water and fat components has to be considered in the extraction of T2 and T2ʹ parameters in many organs. The simultaneous quantification of the proton-density fat fraction (PDFF) can be also of particular interest (e.g. in the liver and in, fat fraction, bone marrow fat fraction). Multi-echo gradient echo imaging can separate water and fat components and quantify PDFF. Therefore, the purpose of the present work was to introduce a novel method for simultaneous T2, T2ʹ and PDFF mapping, relying on an adiabatic T2-preparation combined with a time-interleaved multi-echo gradient echo acquisition scheme.

This abstract and the presentation materials are available to members only; a login is required.

Join Here