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Abstract #0586

Multiparametric Whole-body MRI vs 18FCH-PET-CT in the Primary Staging of Intermediate and High-Risk Prostate Cancer

Edward William Johnston1, Arash Latifoltojar1, Harbir Singh Sidhu1, Navin Ramachandran1, Magdalena Sokolska2, Alan Bainbridge2, Caroline Moore3, Hashim Ahmed3, and Shonit Punwani1

1UCL Centre for Medical Imaging, London, United Kingdom, 2Medical Physics, University College London Hospital, London, United Kingdom, 3Department of Urology, University College Hospital, London, United Kingdom

Whilst whole body MRI is gaining momentum in cancer staging for multiple tumour types, relatively few groups have focused on the primary staging of prostate cancer.

In this study, we evaluated the role of an extensive multiparametric MRI protocol, including diffusion-weighted imaging in 23 patients against an 18F-choline PET-CT/ expert panel based reference standard.

According to the reference standard, we found that whole body MRI provided an equivalently high diagnostic accuracy vs. PET-CT in lymph nodes, and outperformed PET-CT in the detection of bone lesions. However, higher technical error rates suggest MRI reporting experience needs to be developed first.

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