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Abstract #0612

Optimized CS-Wave imaging with tailored sampling and efficient reconstruction

Berkin Bilgic1, Huihui Ye1, Lawrence L Wald1, and Kawin Setsompop1

1Martinos Center for Biomedical Imaging, Charlestown, MA, United States

Wave-CAIPI utilizes additional gradients during the readout to improve controlled aliasing and fully harness coil sensitivity encoding. Recently proposed CS-Wave extended Wave-encoding with Poisson sampling and wavelet regularization. This work proposes optimized CS-Wave with i) tailored data-sampling and ii) highly efficient reconstruction. At 15-fold acceleration, proposed CS-Wave provides 20% RMSE improvement over Wave-CAIPI, which nearly doubles the improvement achieved with previously proposed CS-Wave. This permits single head-orientation Quantitative Susceptibility Mapping at 1×1×2mm3 resolution in 25s. Combining CS-Wave with SMS Echo-Shift strategy further increases the acceleration to 30-fold, thus enabling multi-orientation QSM at long-TE from three head-rotations at 1.5mm isotropic in 72s.

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