Meeting Banner
Abstract #0707

Magnetic Resonance Elastography (MRE) for the assessment of renal allograft function

Jing Guo1, Stephan Marticorena1, Florian Dittmann1, Andreas Fehlner1, Sebastian Hirsch1, Thomas Fischer1, Jürgen Braun2, and Ingolf Sack1

1Radiology, Charité - Universitätsmedizin Berlin, Berlin, Germany, 2Department of Medical Informatics, Charité - Universitätsmedizin Berlin, Berlin, Germany

In vivo assessment of the renal allograft function post kidney transplantation is challenging. We here demonstrate that multifrequency MR elastography (MMRE) can detect renal allograft dysfunction with good diagnostic accuracy (AUROC:0.91 [95% CI 0.80-1.02; p < 0.001]). Renal stiffness is significantly lower in dysfunctional transplant kidney and correlates moderately with glomerular filtration rate and resistive index. MMRE may serve as a non-invasive imaging maker to detect renal allograft dysfunction in an early stage and to monitor renal allograft function longitudinally.

This abstract and the presentation materials are available to members only; a login is required.

Join Here