Abstract #0712

MR Elastography of The Prostate with A Mode-Conversion Endourethral Driver: Feasibility at 3.0 T

Jin Wang¹, Kevin J. Glaser², Bingjun He¹, Tianhui Zhang¹, Jun Pang³, Ziying Yin², Zhuang Kang¹, Qungang Shan¹, Meng Yin², Forghanian-Arani Arvin², and Richard L. Ehman²

¹Department of Radiology, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China, People's Republic of, ²Department of Radiology, Mayo Clinic, Rochester, MN, United States, ³Department of Urology, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China, People's Republic of

Prostate cancer(PCa) is one of the leading causes of cancer-related deaths in men. Detection of clinically significant PCa is a major challenge. We evaluated the feasibility of a novel approach for quantitatively imaging the stiffness of prostate gland, using a conventional urinary catheter as a source of shear waves for MR elastography. Results in 19 examinations showed that the approach, which uses conventional commercially-available MRE drivers can generate shear wave fields in the prostate that are suitable processing. Measurements of regional prostate stiffness in patients with benign prostatic hypertrophy and PCa reveal trends that provide motivation for further evaluation of prostatic MRE.

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