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Abstract #0752

Super-Resolution Magnetic Resonance Elastography (SR-MRE) of Exercise Induced Muscle Damage (EIMD)

M. Perrins1, E. Barnhill2, P. Kennedy1, J. Braun2, I. Sack2, A. Hunter3, C. Brown4, E. van Beek1, and Neil Roberts1

1University of Edinburgh, Edinburgh, United Kingdom, 2Department of Radiology, Charité - Universitätsmedizin Berlin, Berlin, Germany, 3School of Sport, University of Stirling, Stirling, United Kingdom, 4The Mentholatum Company Ltd., East Kilbride, United Kingdom

Super-Resolution (SR) Magnetic Resonance Elastography (MRE) was applied to measure thigh muscle viscoelastic properties in 20 subjects in whom Exercise Induced Muscle Damage (EIMD) was produced using a well-established muscle damage protocol. SR-MRE is made possible by analysing Multi-frequency MRE (MMRE) in a manner such that multiple low-resolution images of the same scene are interpolated and fused to create a single, high-resolution image. Muscle tissue is well suited to study using SR-MRE and the sites of muscle damage could be clearly identified suggesting potential useful clinical applications for the technique. SR-MRE also has potential to provide insight regarding the mechanisms underlying tissue damage in EIMD.

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