Abstract #0752

Super-Resolution Magnetic Resonance Elastography (SR-MRE) of Exercise Induced Muscle Damage (EIMD)

M. Perrins¹, E. Barnhill², P. Kennedy¹, J. Braun², I. Sack², A. Hunter³, C. Brown⁴, E. van Beek¹, and Neil Roberts¹

¹University of Edinburgh, Edinburgh, United Kingdom, ²Department of Radiology, Charité - Universitätsmedizin Berlin, Berlin, Germany, ³School of Sport, University of Stirling, Stirling, United Kingdom, ⁴The Mentholatum Company Ltd., East Kilbride, United Kingdom

Super-Resolution (SR) Magnetic Resonance Elastography (MRE) was applied to measure thigh muscle viscoelastic properties in 20 subjects in whom Exercise Induced Muscle Damage (EIMD) was produced using a well-established muscle damage protocol. SR-MRE is made possible by analysing Multi-frequency MRE (MMRE) in a manner such that multiple low-resolution images of the same scene are interpolated and fused to create a single, high-resolution image. Muscle tissue is well suited to study using SR-MRE and the sites of muscle damage could be clearly identified suggesting potential useful clinical applications for the technique. SR-MRE also has potential to provide insight regarding the mechanisms underlying tissue damage in EIMD.

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