Meeting Banner
Abstract #0773

In Vivo Whole-Brain T1-rho Mapping in evaluation of Mesial Temporal Lobe epilepsy

Xixi Zhao1, Junling Wang1, Xiangliang Tan1, Xiang Xiao1, Jiajun Zhang1, Yingjie Mei2, Queenie Chan3, and Yikai Xu1

1Department of Medical Imaging Center, Nanfang Hospital, Southern Medical University, Guangzhou, China, People's Republic of, 2Philips Healthcare, Guangzhou, China, People's Republic of, 3Philips Healthcare, HongKong, China, People's Republic of

In human brain, T1ρ has been proven to be relevant with the macromolecular composition of tissues, and supposed to be sensitive to neuronal degeneration. We used T1rho MR imaging to investigate the variations in T1rho values of subcortical gray matter structures automatic-drawn using FIRST segmentation among temporal lobe epilepsy patients and the underlying relation between the significantly altered T1rho values or volumes of subcortical structures and duration of epilepsy or age at epilepsy onset. Our results demonstrate the feasibility of ROI-wise analysis by atlas-based segmentation of T1rho imaging among mTLE patients

This abstract and the presentation materials are available to members only; a login is required.

Join Here