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Abstract #0790

False positive bundles in tractography

Maxime Descoteaux1, Jasmeen Sidhu1, Eleftherios Garyfallidis1, Jean-Christophe Houde1, Peter Neher2, Bram Stieltjes3, and Klaus H. Maier-Hein2

1Computer Science, Université de Sherbrooke, Sherbrooke, QC, Canada, 2German Cancer Research Center, Heindeberg, Germany, 3Basel University, Basel University Hospital, Switzerland

This work provides novel insights in false positive bundles produced by tractography using a highly realistic diffusion MRI phantom with known underlying white matter ground truth anatomy. This MRI phantom was used in the ISMRM 2015 Tractography Challenge. We show that regardless of the tractography pipeline used, many invalid bundles with dense and meaningful structures are found in the tractograms.

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