Abstract #0854

High Resolution Diffusion Tensor Imaging for Cervical Spondylotic Myelopathy: A Preliminary Follow-up Study

Yuhui Xiong¹, Xiaodong Ma¹, Xiaolong Chen², Li Guan², Yong Hai², Zhe Zhang¹, Le He¹, Chun Yuan^1,3, and Hua Guo¹

¹Center for Biomedical Imaging Research, Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, China, People's Republic of, ²Department of Orthopedics, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China, People's Republic of, ³Vascular Imaging Laboratory, Department of Radiology, University of Washington, Seattle, WA, United States

As a conventional method in spinal cord assessment in cervical spondylotic myelopathy (CSM) patients, intramedullary high signal intensity (HSI) in T2W images is limited in diagnosis accuracy and predictive capacity for postoperative recovery. Single-shot EPI DTI can detect microstructural information, but it has low image resolution and distortion. In this work, a multi-shot interleaved EPI DTI using SYMPHONY reconstruction method is used to assess the pathologic conditions and the function of spinal cords of CSM patients quantitatively. The results show that the high resolution MS-EPI DTI can performs better than HSI or SS-EPI DTI in CSM diagnosis and recovery monitoring.

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