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Abstract #0876

Improvement in Alignment & Signal Uniformity via Realtime B0 Correction and Image Registration in Multi-station PET/MR Whole body Diffusion Imaging

Maggie Mei Kei Fung1, Abhishek Sharma2, Justin Lahrman3, Lloyd Estkowski4, and Ersin Bayram5

1MR Apps & Workflow, GE Healthcare, New York, NY, United States, 2MR Engineering, GE Healthcare, Bangalore, India, 3MR Apps & Workflow, GE Healthcare, Waukesha, WI, United States, 4MR Apps & Workflow, GE Healthcare, Menlo Park, CA, United States, 5MR Apps & Workflow, GE Healthcare, Houston, TX, United States

In a PET/MR imaging, anatomical alignment between PET & MR images and good visualization of spine & lymph node are critical in the clinical interpretation of diseases. In whole body multi-station diffusion weighted imaging (DWI), it is common to observe signal drop off and spatial misalignment due to B0 inhomogeneity. In this study, we proposed a two-prong approach in improving the signal uniformity & spatial alignment by combining a real-time slice-by-slice B0 correction technique and an image registration technique. We have validated the approach in 18 volunteers with various physical attributes.

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