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Abstract #0878

PET/MR attenuation correction using Zero Echo Time imaging in 15O-water study

Mohammad Mehdi Khalighi1, Gaspar Delso2, Praveen K. Gulaka3, Audrey Peiwen Fan3, Bin Shen4, Aileen Hoehne4, Prachi Singh3, Jun-Hyung Park4, Dawn Holley3, Frederick T. Chin3,4, and Greg Zaharchuk3,4

1Applied Science Lab, GE Healthcare, Menlo Park, CA, United States, 2Applied Science Lab, GE Healthcare, Zurich, Switzerland, 3Radiology Department, Stanford University, Stanford, CA, United States, 4Molecular Imaging Program, Stanford University, Stanford, CA, United States

Accurate identification of bone tissue is important to generate attenuation correction maps on a PET/MR scanner for quantification of tracer activity in PET images. Head atlas-based attenuation correction and a new zero echo time technique (ZTE) for attenuation correction are compared in an 15O-water brain study. The comparison shows that ZTE-based attenuation correction provides more accurate identification of bone tissue and thus of the tracer activity. Any mismatch in bone identification will affect the tracer activity, especially in voxels close to the bone.

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