Abstract #0878

PET/MR attenuation correction using Zero Echo Time imaging in 15O-water study

Mohammad Mehdi Khalighi¹, Gaspar Delso², Praveen K. Gulaka³, Audrey Peiwen Fan³, Bin Shen⁴, Aileen Hoehne⁴, Prachi Singh³, Jun-Hyung Park⁴, Dawn Holley³, Frederick T. Chin^3,4, and Greg Zaharchuk^3,4

¹Applied Science Lab, GE Healthcare, Menlo Park, CA, United States, ²Applied Science Lab, GE Healthcare, Zurich, Switzerland, ³Radiology Department, Stanford University, Stanford, CA, United States, ⁴Molecular Imaging Program, Stanford University, Stanford, CA, United States

Accurate identification of bone tissue is important to generate attenuation correction maps on a PET/MR scanner for quantification of tracer activity in PET images. Head atlas-based attenuation correction and a new zero echo time technique (ZTE) for attenuation correction are compared in an ¹⁵O-water brain study. The comparison shows that ZTE-based attenuation correction provides more accurate identification of bone tissue and thus of the tracer activity. Any mismatch in bone identification will affect the tracer activity, especially in voxels close to the bone.

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