Abstract #1007

Non-contrast Pulmonary Perfusion at 3T using FAIR with inflow saturation and background suppression

Joshua S. Greer^1,2, Yue Zhang², Christopher Maroules², Orhan K. Oz², Ivan Pedrosa^2,3, and Ananth J. Madhuranthakam^2,3

¹Bioengineering, University of Texas at Dallas, Richardson, TX, United States, ²Radiology, UT Southwestern Medical Center, Dallas, TX, United States, ³Advanced Imaging Research Center, UT Southwestern Medical Center, Dallas, TX, United States

Flow Alternating Inversion Recovery (FAIR) has been studied extensively for pulmonary perfusion imaging at 1.5T, but suffers from low SNR, and is often corrupted by bright signal in the major vasculature and image misregistration artifacts due to respiratory motion. The purpose of this study was to evaluate FAIR at 3T for increased SNR and compare against SPECT perfusion, to combine FAIR with inflow saturation to reduce signal in the major pulmonary vessels, and to combine FAIR with background suppression strategies to minimize artifacts due to image misregistration.

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