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Abstract #1010

Multi-Dimensional Reduced Field-of-View Excitation by Integrated RF Pulse and DYNAMITE B0 Field Design

Suryanarayana Umesh Rudrapatna1, Robin de Graaf1, Terrance Nixon1, and Christoph Juchem1

1Yale University, New Haven, CT, United States

Spatially selective multi-dimensional excitation with large flip angles is challenging, as current RF pulse design methods are computationally involved and typically yield low time-bandwidth product (TB < 10) pulses. The difficulty stems from Bloch equation non-linearity and the inflexibility in B0 pattern generation using linear gradients. This study uses the dynamic multi-coil technique (DYNAMITE), that provides unprecedented B0 shaping flexibility, facilitating the use of 1-dimensional Shinnar-Le Roux (SLR) pulses for 2-dimensional excitation. Selective mouse brain excitation was accomplished by adaptively designing the SLR pulse and the underlying B0 fields generated by DYNAMITE. The resultant zoomed MRI achieved more than two-fold acquisition acceleration at < 4% undesired excitation with TB > 12 pulses.

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