Abstract #1010

Multi-Dimensional Reduced Field-of-View Excitation by Integrated RF Pulse and DYNAMITE B0 Field Design

Suryanarayana Umesh Rudrapatna¹, Robin de Graaf¹, Terrance Nixon¹, and Christoph Juchem¹

¹Yale University, New Haven, CT, United States

Spatially selective multi-dimensional excitation with large flip angles is challenging, as current RF pulse design methods are computationally involved and typically yield low time-bandwidth product (TB < 10) pulses. The difficulty stems from Bloch equation non-linearity and the inflexibility in B₀ pattern generation using linear gradients. This study uses the dynamic multi-coil technique (DYNAMITE), that provides unprecedented B₀ shaping flexibility, facilitating the use of 1-dimensional Shinnar-Le Roux (SLR) pulses for 2-dimensional excitation. Selective mouse brain excitation was accomplished by adaptively designing the SLR pulse and the underlying B₀fields generated by DYNAMITE. The resultant zoomed MRI achieved more than two-fold acquisition acceleration at < 4% undesired excitation with TB > 12 pulses.

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