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Abstract #1112

Whole brain in-vivo g-ratio mapping using neurite orientation dispersion and density imaging (NODDI) and GRE myelin water imaging (GRE-MWI)

Woojin Jung1, Yoonho Nam2, Hui Zhang3, and Jongho Lee1

1Laboratory for Imaging Science and Technology, Department of Electrical and Computer Engineering, Seoul National University, Seoul, Korea, Republic of, 2Department of Radiology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea, Republic of, 3Department of Computer Science & Centre for Medical Image Computing, University College London, London, United Kingdom

A new in-vivo g-ratio mapping method that combined neurite orientation dispersion and density imaging (NODDI) and GRE myelin water imaging (GRE-MWI) is proposed. The method is substantially fast, taking 17 min for a 2 mm isotropic resolution whole brain g-ratio mapping. The resulting map reveals a reasonable range of g-ratio that has been reported in histology studies.

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