Abstract #1112

Whole brain in-vivo g-ratio mapping using neurite orientation dispersion and density imaging (NODDI) and GRE myelin water imaging (GRE-MWI)

Woojin Jung¹, Yoonho Nam², Hui Zhang³, and Jongho Lee¹

¹Laboratory for Imaging Science and Technology, Department of Electrical and Computer Engineering, Seoul National University, Seoul, Korea, Republic of, ²Department of Radiology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea, Republic of, ³Department of Computer Science & Centre for Medical Image Computing, University College London, London, United Kingdom

A new in-vivo g-ratio mapping method that combined neurite orientation dispersion and density imaging (NODDI) and GRE myelin water imaging (GRE-MWI) is proposed. The method is substantially fast, taking 17 min for a 2 mm isotropic resolution whole brain g-ratio mapping. The resulting map reveals a reasonable range of g-ratio that has been reported in histology studies.

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