Abstract #1126

A feasibility study to perform combined MR Elastography, IVIM and DCE-MRI in pancreatic cancer patients.

Jurgen H Runge¹, Remy Klaassen², Oliver J Gurney-Champion^1,3, Hanneke WM van Laarhoven², Ralph Sinkus⁴, Aart J Nederveen¹, and Jaap Stoker¹

¹Radiology, Academic Medical Center, Amsterdam, Netherlands, ²Medical Oncology, Academic Medical Center, Amsterdam, Netherlands, ³Radiation Oncology, Academic Medical Center, Amsterdam, Netherlands, ⁴Biomedical Engineering, King's College London, London, United Kingdom

Pancreatic cancer remains one the most deadly cancers. New therapeutic agents cause confusion as prior morphological criteria to determine the presence of a response appear to be unreliable. MR Elastography (MRE) is uniquely able to determine tissue stiffness, a property potentially useful for therapy response monitoring. Here we present our first preliminary results of combining MRE with IVIM and DCE MRI.

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