Abstract #1134

High-Resolution Single-Point qMT of the Lumbar Cord

Alex K. Smith^1,2, Richard D. Dortch^1,2,3, Samantha By^1,2, Robert L. Barry², Chris R. Thompson², Kristen George-Durrett², Bailey D. Lyttle², and Seth A. Smith^1,2,3

¹Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, United States, ²Vanderbilt University Institute of Imaging Science, Vanderbilt University, Nashville, TN, United States, ³Department of Radiology and Radiological Sciences, Vanderbilt University, Nashville, TN, United States

The spinal cord is responsible for mediating neurologic function, and in particular, the lumbar cord is integral to lower extremity function. However, lumbar cord quantitative MRI studies have been limited due to its size, location, and composition. A single-point quantitative magnetization transfer was recently developed, but has not been applied to the lumbar cord. Therefore, we have implemented an assessment of qMT at the thoracolumbar bulge to characterize the MT effect in the thoracolumbar cord in healthy volunteers.

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