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Abstract #1322

SHINKEI Quant: Simultaneous Acquisition of MR Neurography and T2 Mapping for Quantitative Evaluation of Chronic Inflammatory Demyelinating Polyneuropathy

Masami Yoneyama1, Osamu Togao2, Akio Hiwatashi2, Yuriko Ozawa3, Makoto Obara1, Tomoyuki Okuaki4, and Marc Van Cauteren4

1Philips Electronics Japan, Tokyo, Japan, 2Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan, 3Yaesu Clinic, Tokyo, Japan, 4Philips Healthcare Asia Pacific, Tokyo, Japan

MR neurography achieves selective depiction of peripheral nerves and detects pathological changes related to neuropathies as a signal abnormality. Recently, we proposed a novel MR neurography sequence (SHINKEI) that provides high-quality MR neurography in the brachial plexus and the lumbosacral plexus. However, SHINKEI could not quantitatively assess the nerve pathology. In this study, we developed a new sequence (SHINKEI-Quant) to simultaneously acquire MR neurography and T2 mapping by further optimizing the iMSDE preparation. SHINKEI-Quant could simultaneously provide both MR neurography and T2 maps without prolongation of acquisition time compared with the conventional SHINKEI sequence. This quantitative sequence may be helpful to quantitatively assess the nerve pathology such as chronic inflammatory demyelinating polyneuropathy.

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