Meeting Banner
Abstract #1324

Non-Gaussian diffusion weighted imaging in the head and neck; how we can improve the clinical diagnostic accuracy beyond ADC

Mami Iima1,2, Akira Yamamoto1, Shigeru Hirano3, Ichiro Tateya3, Morimasa Kitamura3, and Kaori Togashi1

1Department of Diagnostic Imaging and Nuclear Medicine, Graduate Schoolof Medicine, Kyoto University, Kyoto, Japan, 2The Hakubi Center for Advancer Research, Kyoto University, Kyoto, Japan, 3Department of Otolaryngology, Graduate Schoolof Medicine, Kyoto University, Kyoto, Japan

The usefulness of non-Gaussian diffusion parameters for the clinical diagnostic ability in the head and neck was evaluated. 135 (62 malignant/63 benign/10 inflammation) patients were prospectively recruited, and non-Gaussian DWI and IVIM parameters as well as synthetic ADC, which comprises both Gaussian and non-Gaussian effect, were estimated from the DWI datasets with multiple b values. Significant difference in each parameter was observed between malignant and benign lesions. There was a significant difference between inflammation or lymphatic vascular malformation and tumors in K or fIVIM values, providing the potential to improve the DWI diagnostic accuracy by complementing their diagnostic abilities.

This abstract and the presentation materials are available to members only; a login is required.

Join Here