Xiaofeng Tao1, gongxin yang1, Yingwei Wu2, huimin shi1, pingzhong wang1, yongming Dai3, wenjing zhu1, Weiqing gao1, and qiang yu1
1Shanghai Ninth People’s Hospital, School of Medicine, Shanghai Jiao Tong University, shanghai, China, People's Republic of, 2Shanghai Ninth People’s Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China, People's Republic of, 3PHLIPS healthcare China, shanghai, China, People's Republic of
The
aim of this study was to determine the value of combining conventional MR
imaging (MRI), diffusion-weighted (DW-MRI) and dynamic contrast enhanced MRI
(DCE-MRI) in diagnosing solid neoplasms in the parotid gland.
Materials and Methods：A total of 148 subjects (101 with benign
and 47 with malignant tumors) were evaluated with conventional MRI, DW-MRI and
DCE-MRI prior to surgery and pathologic verification. The items observed with
conventional MRI included the shape, capsule and signal intensity of parotid
masses. The apparent diffusion coefficient (ADC) was calculated from DW-MRI that was obtained with a b factor of 0 and
1000 s/mm2. A time-intensity curve (TIC) was
obtained from DCE-MRI.
Results：There were significant differences
(p<0.01) in the shape, capsule, ADC and TIC between benign and malignant
parotid tumors. Irregular neoplasms without capsule, ADC < 1.12×10-3mm2/s, and a plateau enhancement pattern
were valuable parameters for predicting malignant neoplasms. A combination of all
of these parameters yielded sensitivity, specificity, accuracy, and positive
and negative predictive values of 85.1%, 94.1%, 91.2%, and 87.0% and 93.1%,
respectively.
Conclusion：A combined
analysis using conventional MRI, DW-MRI and DCE-MRI is helpful to distinguish
benign from malignant tumors in the parotid gland.
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