Abstract #1456

Combing fMRI and probabilistic DTI tractography to improve corticospinal tract visualization in patients with brain tumor

Chen Niu¹, Xin Liu², Pan Lin², Zhigang Min¹, Wenfei Li¹, Liping Guo¹, Maode Wang¹, Qi Li¹, and Ming Zhang¹

¹Department of Medical Imaging, The First Affiliated Hospital of Xi'An Jiaotong University, Xi'an, China, People's Republic of, ²Institute of Biomedical Engineering, Xi'an Jiaotong University, Xi'an, China, People's Republic of

we evaluated a combinatorial approach that used functional activation and anatomical landmark data to define multiple ROIs for CST fiber tracking in patients with a brain tumor. Our results suggest that a combination of fMRI and DTI fiber tracking may provide a more comprehensive analysis of the CST pathway, which would be beneficial for characterizing spatial relationships between the CST pathway and the tumor. A dual ROI CST fiber tracking approach has the potential to play a critical role in preoperative planning to optimize surgical treatment and improve post-surgical outcome.

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