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Abstract #1456

Combing fMRI and probabilistic DTI tractography to improve corticospinal tract visualization in patients with brain tumor

Chen Niu1, Xin Liu2, Pan Lin2, Zhigang Min1, Wenfei Li1, Liping Guo1, Maode Wang1, Qi Li1, and Ming Zhang1

1Department of Medical Imaging, The First Affiliated Hospital of Xi'An Jiaotong University, Xi'an, China, People's Republic of, 2Institute of Biomedical Engineering, Xi'an Jiaotong University, Xi'an, China, People's Republic of

we evaluated a combinatorial approach that used functional activation and anatomical landmark data to define multiple ROIs for CST fiber tracking in patients with a brain tumor. Our results suggest that a combination of fMRI and DTI fiber tracking may provide a more comprehensive analysis of the CST pathway, which would be beneficial for characterizing spatial relationships between the CST pathway and the tumor. A dual ROI CST fiber tracking approach has the potential to play a critical role in preoperative planning to optimize surgical treatment and improve post-surgical outcome.

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