Pseudo continuous arterial spin labeling (pCASL)
studies can be degraded by
magnetic field variations at the labeling plane. We demonstrate through
simulations that high velocity efficiency is particularly vulnerable to field
offsets. By changing labeling parameters from published recommendations and/or
introducing a new RF pulse, the off-resonance sensitivity and peak systolic
velocity sensitivity of pCASL can be reduced. Preliminary experimental
comparisons of parameters are reported.