Abstract #1546

Echo time based influences on quantitative susceptibility mapping

Surabhi Sood¹, Javier Urriola¹, David Reutens¹, Steffen Bollmann¹, Kieran O'Brien², Markus Barth¹, and Viktor Vegh¹

¹Centre for Advanced Imaging, The University of Queensland, Brisbane, Australia, ²Siemens Ltd., Brisbane, Australia

Quantitative susceptibility mapping is an important magnetic resonance imaging tool which can help define brain structure and composition. Our work aims to explore information contained in the temporal trend by analysing the mapped magnetic susceptibility as a function of echo time from gradient recalled data acquired at 7T. Temporal susceptibility plots were studied in ten brain regions. Parameterisation of image voxel susceptibility compartments has the potential to delineate structural and chemical changes in tissue and formulate biologically meaningful measures. This in turn provides a framework for new imaging biomarker developments in neurodegenerative diseases and disorders affecting the central nervous system.

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