Abstract #1563

Simultaneous water content, electrical conductivity and susceptibility mapping in meningiomas on a 3T MR-PET scanner

YP Liao¹, A.-M. Oros-Peusquens¹, J. Lindemeyer¹, N. Lechea¹, C. Weiss², G. Stoffels¹, C. Filss¹, K.J. Langen¹, and N.J. Shah^1,3

¹Institute of Neuroscience and Medicine-4, Forschungszentrum Juelich, Juelich, Germany, ²Department of Neurosurgery, University of Cologne, Cologne, Germany, ³Department of Neurology, JARA, Faculty of Medicine, RWTH Aachen University, Aachen, Germany

The availability of combined MR-PET scanners opens new opportunities for the characterisation of the tumour environments. In this study, MR-based simultaneous water content, electrical conductivity and susceptibility mapping in meningioma patients was implemented based on a multi-echo gradient echo sequence. The information was complemented by characterisation of the tumour with simultaneous FET-PET. This is a powerful combination of parameters which reflect important aspects of tissue physiology and also characterise to a large extent, tumour electromagnetic (EM) properties. This multi-parametric information helps to understand pathological tissue and can be applied to planning nonionizing EM hyperthermia therapy.

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