Abstract #1582

Combined Intravoxel Incoherent Motion and Diffusion Tensor Imaging for Evaluation Renal Changes in Diabetic Nephropathy

Cheng long Wen¹, Lihua Chen¹, Fan Mao¹, Yu Zhang², and Wen Shen¹

¹Department of Radiology, Tianjin First Center Hospital, Tianjin, China, Tianjin, China, People's Republic of, ²Philips healthcare, Beijing, China., Beijing, China, People's Republic of

The goal of this pilot study was to assess the ADC value in kidney of IVIM and DTI in distinguishing diabetic subjects and healthy controls. In our study, cortical ADC and D of patients with DN were significantly lower than those of healthy controls. The reduction of D values in the cortex and medulla was more obvious than ADC in patients. The results of this study suggested that cortical D and ADC, quantified by kidney IVIM and DTI could be potential imaging biomarkers for DN. IVIM could reflect the renal function more sensitive and accurate in DN patients.

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